Apolipoprotein E and protection against hepatitis E viral infection in American non-Hispanic blacks

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Apolipoprotein E and protection against hepatitis E viral infection in American non-Hispanic blacks.

UNLABELLED Hepatitis E viral (HEV) infection imposes a heavy health burden worldwide and is common in the United States. Previous investigations of risks addressed environmental and host behavioral/lifestyle factors, but host genetic factors have not been examined. We assessed strength of associations between antibody to HEV (anti-HEV) immunoglobulin G seropositivity indicating past or recent H...

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CASE PRESENTATION A 63-year-old Indian man presented to the emergency department with fever, nausea, chills, and generalized abdominal pain that had been present for 2 weeks. Th e patient had been in India for the past 3 months and began to feel ill during the last week of his visit. He was seen by a local physician and was found to have abnormal liver function tests and was treated with sparfl...

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Role of HLA-B7, B8, B27, and B51 in Protection against Hepatitis B Virus Infection

Background: It has been arguedthat unprecedented degree of human leukocyte antigen (HLA) loci polymorphism within a population is requiredto avoid the devastating effects of infectious diseases. The present study was conducted to determine the associations between some of HLA classI genes and the outcome of hepatitis B virus (HBV) infection. Methods: Using sequential sampling method, 64 individ...

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Background and Aims: Hepatitis E virus (HEV) is considered as one of the common causes of acute viral hepatitis in the world, particularly in the developing countries. It also causes fulminant hepatitis in pregnant women. Although HEV infection in Iran is endemic, there are numerous reports of epidemics caused by this infection in this part of the world. This study aimed to determine seropreval...

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ژورنال

عنوان ژورنال: Hepatology

سال: 2015

ISSN: 0270-9139

DOI: 10.1002/hep.27938